(GoHealthier.com) –
Hollywood is renowned for creating diet crazes, and some of these weight-loss trends can be downright dangerous. One of these seemingly magical elixirs is in the spotlight now: semaglutide, which is prescribed under the brand names Ozempic and Wegovy. This drug was originally developed to help manage type 2 diabetes, but its off-brand use for weight loss skyrocketed its use and popularity. A long list of celebrities have admitted to being on it, including: Oprah, Rosie O’Donell, Tracy Morgan, and Elon Musk, to name a few. While Ozempic and Wegovy can be incredibly effective, and the dramatic weight loss results can be seductive, there are a host of potential health risks associated with its use:
1. Gastrointestinal Issues
– Common Side Effects: Nausea, vomiting, diarrhea, constipation, and abdominal pain are the most frequently reported side effects.
– Why it happens: Ozempic works by slowing gastric emptying and reducing appetite, which can lead to these gastrointestinal symptoms.
2. Pancreatitis
– Risk: There is a risk of developing pancreatitis, an inflammation of the pancreas, which can be serious and potentially life-threatening.
– Symptoms to watch for: Severe abdominal pain that may radiate to the back, nausea, and vomiting. If these occur, medical attention is necessary.
3. Thyroid Tumors
– Risk: In animal studies, semaglutide has been shown to cause thyroid C-cell tumors, including medullary thyroid carcinoma (MTC).
– Human Impact: While it’s unclear if this risk applies to humans, people with a personal or family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2) should avoid using semaglutide.
4. Hypoglycemia (Low Blood Sugar)
– Risk: Although Ozempic and Wegovy themselves have a low risk of causing hypoglycemia, the risk increases when used in combination with other medications, such as insulin or sulfonylureas.
– Symptoms to watch for: Dizziness, sweating, confusion, and fainting.
5. Kidney Injury
– Risk: Semaglutide can cause dehydration due to gastrointestinal side effects like vomiting and diarrhea, potentially leading to acute kidney injury.
– Precautions: Stay well-hydrated, especially if experiencing gastrointestinal symptoms.
6. Gallbladder Disease
– Risk: There is an increased risk of developing gallbladder disease, including gallstones, which can lead to cholecystitis (inflammation of the gallbladder).
– Symptoms to watch for: Sudden severe abdominal pain, fever, and jaundice.
7. Allergic Reactions
– Risk: Some individuals may experience serious allergic reactions, including anaphylaxis, which is life-threatening.
– Symptoms to watch for: Rash, itching, swelling, severe dizziness, and trouble breathing.
8. Increased Heart Rate
– Risk: Some users may experience an increase in heart rate. This could be concerning for people with cardiovascular issues.
– Monitoring: It’s important to monitor heart rate, especially in individuals with existing heart conditions.
9. Possible Mental Health Effects
– Emerging Concerns: Some users have reported mood changes, anxiety, and depression, although these effects are not well-studied.
– Recommendation: Monitor mental health closely and consult a healthcare provider if any psychological symptoms emerge.
10. Long-Term Safety Unknown
– Concerns: Since Ozempic and Wegovy are relatively new to the market, the long-term effects, especially when used for weight loss, are not fully understood.
– Caution: Prolonged use should be closely monitored by a healthcare provider, particularly if used off-label for weight loss.
While the allure of a quick fix for weight loss is beyond enticing, it is essential to discuss potential risks and benefits with your healthcare provider, especially if using semaglutide for weight loss rather than its primary indication of managing type 2 diabetes. Many people, including celebrities, are beginning to speak out about their negative experiences with this drug, and anyone considering taking it for weight loss should take note.
